Christopher R. Reisch

Characterizing constitutive promoters across the Proteobacteria

The paper identifies and characterizes constitutive promoters across three Proteobacteria classes, showing their expression range and portability between hosts.

Comparative Genomics and Directed Evolution Reveal Genetic Determinants of Extreme UVC Radiation Tolerance in Bacteria Recovered from the Stratosphere

This study identifies genetic factors contributing to extreme UVC radiation tolerance in stratospheric bacteria through comparative genomics and directed evolution.

Broad-host-range mutagenesis with CRISPR-associated transposase

This paper introduces a broad-host-range CRISPR-associated transposase (CasTn) system for efficient targeted mutagenesis and transposon insertion in Proteobacteria.

GuideMaker: Software to design CRISPR-Cas guide RNA pools in non-model genomes

GuideMaker designs CRISPR-Cas guide RNA pools for non-model genomes and non-standard Cas enzymes, enabling rapid genome-wide screening.

Potential For Applying Continuous Directed Evolution To Plant Enzymes

The paper discusses two systems for continuous directed evolution of enzymes and tests their adaptation for plant enzyme engineering.