MicrobiologyNucleic Acids ResearchPeer-reviewed
Coronavirus NSP14 Drives Internal m7G Modification to Rewire Host Splicing and Promote Viral Replication
Ensueño Esmeralda Sáenz Altamirano, Chien-Hsin Huang, Yueh-Lin Tsai…·Jack Chun-Chieh Hsu
This study identifies NSP14's role in inducing internal m7G modification in host mRNA, disrupting splicing and promoting SARS-CoV-2 replication, with implications for therapeutic targeting.
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