Author

Martin O. Bergö

Karolinska InstitutetORCID 0000-0002-6915-7140Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1 Assay:proteomics· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Alex RaterinkiD· 1 shared Angela JeongiD· 1 shared Anna‐Karin GustavssoniD· 1 shared David Alan BennettiD· 1 shared Gabriella GaglianoiD· 1 shared Ling LiiD· 1 shared Rui ZhongiD· 1 shared Shaowu ChengiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 16 mutual co-author links

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1 shared paperBiophysics

Alex RaterinkORCID

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2 papers

Recent·Most cited

Increased Telomere Mobility in Progeria is Restored by Isoprenylcysteine Carboxyl Methyltransferase Inhibition

Gabriella Gagliano, Alex Raterink, Xijie Yang, Martin O. Bergö, Anna‐Karin Gustavsson

This study quantifies telomere dynamics in HGPS patient fibroblasts and shows that C75 fully restores chromatin dynamics while Lonafarnib only partially rescues them.

bioRxiv · Apr 28, 2026 · PreprintBiophysics

Protein farnesylation is upregulated in Alzheimer's human brains and neuron-specific suppression of farnesyltransferase mitigates pathogenic processes in Alzheimer's model mice

Angela Jeong, Shaowu Cheng, Rui Zhong, David Alan Bennett, Martin O. Bergö, Ling Li

The paper investigates the role of farnesyltransferase (FT) in Alzheimer's disease by analyzing human brain tissue and generating a mouse model with neuronal FT knockout, finding increased FT and farnesylation in AD and showing mitigation of pathology with FT suppression.

Acta Neuropathologica Communications · Jul 27, 2021Peer-reviewedNeuroscience