Author

Shaowu Cheng

University of MinnesotaORCID 0000-0001-9059-4727Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Angela JeongiD· 1 shared David Alan BennettiD· 1 shared Ling LiiD· 1 shared Martin O. BergöiD· 1 shared Rui ZhongiD· 1 shared

Activity by Year

2021-2021 · peak 1/yr

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5 top collaborators · 10 mutual co-author links

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1 shared paperNeuroscience

Angela JeongORCID

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1 paper

Recent·Most cited

NeuroscienceActa Neuropathologica CommunicationsPeer-reviewedJul 27, 2021

Protein farnesylation is upregulated in Alzheimer's human brains and neuron-specific suppression of farnesyltransferase mitigates pathogenic processes in Alzheimer's model mice

Angela Jeong, Shaowu Cheng, Rui Zhong…·Ling Li

The paper investigates the role of farnesyltransferase (FT) in Alzheimer's disease by analyzing human brain tissue and generating a mouse model with neuronal FT knockout, finding increased FT and farnesylation in AD and showing mitigation of pathology with FT suppression.

31 citations

humanmouse

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