Shao‐Xing Dai

DPCGS: a computational framework for linking GWAS to single-cell transcriptomics in complex traits and diseases

DPCGS links GWAS to single-cell transcriptomics to identify trait-associated cell subpopulations and regulatory programs with higher accuracy than existing methods.

Deciphering molecular heterogeneity and dynamics of human hippocampal neural stem cells at different ages and injury states

The paper analyzes single-nucleus data from the human hippocampus across different ages and injury states to study NSC heterogeneity and dynamics, identifying new markers and revealing quiescence patterns.

Multi-omics integrated analysis reveals a specific phenotype of CD8+ T cell may contribute to immunothromosis via Th17 response in severe and critical COVID-19

The paper identifies a specific CD8+ T cell phenotype in severe COVID-19 linked to Th17 response and immunothrombosis using multi-omics data.

Anti-HIV activity prediction and enrichment identify novel human targets for Anti-HIV therapy

The paper predicts anti-HIV compounds and identifies novel human targets for anti-HIV therapy using a prediction tool and enrichment analysis.

Efficient repositioning of approved drugs as anti-HIV agents using Anti-HIV-Predictor

The paper develops a web server to predict anti-HIV activity of compounds and identifies 7 approved drugs repurposed as anti-HIV agents.