Huan Chen

This study identifies NORAD as a regulator of axonal transport through liquid-liquid phase separation, showing its role in SFPQ transport and neuronal function.

This study identifies MsyB as a HU inhibitor and β-clamp binder in E. coli, showing it modulates DNA supercoiling to influence transcription and adaptive mutation under stress.

FAPM improves protein functional annotation by combining protein sequence and language models, outperforming sequence-only methods on benchmarks and phage proteins with few homologs.

The paper develops a web server to predict anti-HIV activity of compounds and identifies 7 approved drugs repurposed as anti-HIV agents.