The consequences of array size for human centromere performance in mitosis
Ayantika Sen Gupta, Siddharth Shivanandan, Mark Mattingly, Jay R. Unruh, Sean McKinney, Arundhathy Prasanthy Jithesh, Simona Giunta, Jennifer L. Gerton
This study investigates how variations in centromeric alpha-satellite array size affect centromere function during mitosis, finding that smaller arrays are more prone to missegregation and cohesion fatigue.
bioRxiv · Jun 16, 2026 · PreprintCell Biology