Xi Chen

Volumetric Denoising: An Approach to Boost Acquisition and Downstream Analysis of Volume Electron Microscopy

This paper develops a volumetric denoising approach to improve VEM acquisition speed and downstream analysis by optimizing resolution and noise handling.

Fear memory-associated synaptic and mitochondrial changes revealed by deep learning-based processing of electron microscopy data

The paper uses deep learning to analyze electron microscopy data from mouse auditory cortex, revealing structural changes in synapses and mitochondria associated with fear memory.

Scalable volumetric imaging for ultrahigh-speed brain mapping at synaptic resolution

This paper introduces a light-sheet microscopy method for fast, large-scale volumetric brain imaging at synaptic resolution, achieving whole mouse brain scans in 2 hours.