Yvette I. Sheline

HARMONY: A large-scale harmonized neuroimaging dataset for research on anxious misery disorders

HARMONY harmonizes neuroimaging data from multiple cohorts to study brain-behavior associations in anxious misery disorders, showing increased statistical power in pooled analyses.

Electroconvulsive therapy generates a postictal wave of spreading depolarization in mice and humans

This study shows that electroconvulsive therapy (ECT) induces a postictal wave of spreading depolarization in both mice and humans, suggesting a new mechanism for its therapeutic effects.

Resting fMRI-guided TMS evokes subgenual anterior cingulate response in depression

This study shows that targeting cortical areas with high resting state functional connectivity to the sgACC with TMS leads to stronger sgACC responses in depressed patients.

Cortical-subcortical structural connections support transcranial magnetic stimulation engagement of the amygdala

This study shows that transcranial magnetic stimulation (TMS) applied to the ventrolateral prefrontal cortex (vlPFC) modulates amygdala activity via cortical-subcortical connections, suggesting potential therapeutic applications for affective disorders.

Development of a novel connectivity-based electric-field modelling approach for individualized targeting of transcranial magnetic stimulation treatment.

The paper develops a connectivity-based electric-field modelling approach to identify individualized TMS targets for depression treatment by combining rsFC and e-field simulations.

Differential impact of transdiagnostic, dimensional psychopathology on multiple scales of functional connectivity

The paper examines how different psychopathology dimensions affect various scales of brain functional connectivity using multiple modeling approaches.

Longitudinal ComBat: A Method for Harmonizing Longitudinal Multi-scanner Imaging Data

The paper introduces longitudinal ComBat to harmonize multi-scanner imaging data, showing it improves detection of longitudinal changes and controls type I error better than existing methods.

Closed-loop fMRI neurofeedback to reduce negative attentional bias in depression

This study uses closed-loop fMRI neurofeedback to reduce negative attentional bias in depression, showing decreased bias and depression severity after training.

Harmonization of cortical thickness measurements across scanners and sites

ComBat, an empirical Bayes location-and-scale model from genomics, removes additive and multiplicative scanner effects from regional cortical thickness across 11 scanners while preserving age associations.