Gabriel A. Al‐Ghalith

XTree enables memory-efficient, accurate short and long sequence alignment to millions of genomes across the tree of life

XTree aligns sequencing reads to large genome databases efficiently and accurately, outperforming existing tools in precision and recall.

Modular metagenomic analysis of pan-domain symbioses with MAGUS

The paper introduces MAGUS, a toolkit for analyzing metagenomic data from eukaryote-dominated symbiotic communities, and demonstrates its ability to resolve multiple genomes and gene catalogs from coral and hydrozoan samples.

BURST enables mathematically optimal short-read alignment for big data

Exhaustive gapped short-read aligner BURST returns all optimal matches above an identity cutoff, with tie-breaking or LCA taxonomy, at 1,000,000 reads/minute against 5,500 prokaryotic genomes (32 cores).

Evaluating the information content of shallow shotgun metagenomics

This study evaluates shallow shotgun sequencing as an alternative to 16S for affordable, high-resolution human microbiome analysis, finding it provides accurate taxonomic and functional profiles.