Brett Farthing

XTree enables memory-efficient, accurate short and long sequence alignment to millions of genomes across the tree of life

XTree aligns sequencing reads to large genome databases efficiently and accurately, outperforming existing tools in precision and recall.

Highly accurate metagenome-assembled genomes from human gut microbiota using long-read assembly, binning, and consolidation methods

This study improves metagenome-assembled genomes from human gut microbiota using long-read sequencing and novel assembly methods, yielding more high-quality MAGs and uncovering uncultured diversity.