Author

Jamie S. Mitchell

National Hospital for Neurology and NeurosurgeryORCID 0000-0002-6954-9988Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Neuroscience· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Doaa M. TahaiD· 2 shared Giulia E. TyzackiD· 2 shared Ione Meyer· 2 shared Jernej UleiD· 2 shared Jia NewcombeiD· 2 shared Linda GreensmithiD· 2 shared Nicholas M. LuscombeiD· 2 shared Raphaëlle LuisieriD· 2 shared

Activity by Year

2018-2019 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersNeuroscience

Doaa M. TahaORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Widespread FUS mislocalization is a molecular hallmark of ALS

Giulia E. Tyzack, Raphaëlle Luisier, Doaa M. Taha, Jacob Neeves, Miha Modic, Jamie S. Mitchell, Ione Meyer, Linda Greensmith, Jia Newcombe, Jernej Ule, Nicholas M. Luscombe, Rickie Patani

The paper investigates FUS mislocalization in ALS, finding it occurs in both VCP-mutation related and sporadic ALS, and links it to aberrant intron retention in SFPQ transcripts.

bioRxiv · Apr 9, 2019 · PreprintNeuroscience

Post-transcriptional remodelling is temporally deregulated during motor neurogenesis in human ALS models

Raphaëlle Luisier, Giulia E. Tyzack, Claire E. Hall, Jamie S. Mitchell, Helen E. Devine, Doaa M. Taha, Bilal Ahmad Malik, Ione Meyer, Linda Greensmith, Jia Newcombe, Jernej Ule, Nicholas M. Luscombe, Rickie Patani

The paper identifies post-transcriptional changes during motor neurogenesis in ALS models, showing premature intron retention in VCP-mutant cells and similar effects in SOD1 and FUS mutations.

Nature Communications · May 16, 2018Peer-reviewedNeuroscience