Qing Lü

PSTP: Decoding Latent Sequence Grammar for Protein Phase Separation through Transfer Learning and Attention

PSTP predicts protein phase separation regions using transfer learning and attention, achieving 84% accuracy on PhaSePro and improving correlation coefficients over existing models.

Comparative genomics of macaques and integrated insights into genetic variation and population history

This study presents genome assemblies and analyses of macaques to explore genetic variation, population history, and evolutionary differences between species and humans.

Decoding Missense Variants by Incorporating Phase Separation via Machine Learning

PSMutPred predicts the impact of missense variants on phase separation using machine learning, improving the interpretation of variants of unknown significance in intrinsically disordered regions.

CIB2 as a Ca2+ Sensor for Auditory Mechano-Electrical Transduction and Linked to Genetic-Heterogeneity of TMC1 in Hearing Loss

This study identifies CIB2 as a Ca2+ sensor in auditory mechano-electrical transduction and links TMC1 genetic variants to hearing loss through structural and functional analysis.

Structurally divergent and recurrently mutated regions of primate genomes

The paper identifies structurally divergent regions in primate genomes and quantifies the impact of structural variants across multiple species.

A refined characterization of large-scale genomic differences in the first complete human genome

The paper identifies and categorizes large-scale genomic differences between the T2T-CHM13 and GRCh38 human genome assemblies, highlighting their implications for disease and evolution.