Luke R. Green

Emergence of short-lived meningococci causing focal epidemics can be associated with gene transfer from carriage-associated Neisseria

A 21-case nightclub-linked meningococcal outbreak variant differed from its closest relatives by horizontal gene transfer from carriage-associated Neisseria, affecting iron acquisition and type IV pili genes.

Dynamics of the CD9 interactome during bacterial infection of epithelial cells by proximity labelling proteomics

The paper identifies the CD9 interactome in epithelial cells during bacterial infection, showing species-specific interactions and demonstrating a CD9-derived peptide can block bacterial adherence.

Simple Sequence Repeats Mediate Phase Variation of the Mucoid Phenotype in Hypervirulent Klebsiella pneumoniae

This study identifies simple sequence repeats in rmpA and rmpD/rmpC genes that mediate phase variation of the mucoid phenotype in hypervirulent Klebsiella pneumoniae, enabling adaptation to different infection niches.

periscope: Sub-Genomic RNA Identification in SARS-CoV-2 Genomic Sequencing Data

Periscope identifies and quantifies sub-genomic RNAs in SARS-CoV-2 genomic data, detecting canonical and non-canonical sgRNAs with high fidelity.

Altered Subgenomic RNA Expression in SARS-CoV-2 B.1.1.7 Infections

The paper shows that B.1.1.7 SARS-CoV-2 lineage has increased subgenomic RNA expression compared to other lineages, with a noncanonical sgRNA near ORF9b showing a 16-fold increase in median expression.