Author

Danielle Groves

University of Sheffield

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:benchmarking· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Approach:statistical model· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Adrian Deng· 2 shared Jeremy R KeowniD· 2 shared Nicole C RobbiD· 2 shared Abha ChopraiD· 1 shared Adrienn AngyaliD· 1 shared Alain KohliD· 1 shared Alexander J Keeley· 1 shared Ana Da Silva FilipeiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersMicrobiology

Adrian Deng

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Molecular and Structural Characterisation of the MERS-Coronavirus Polymerase

Rory F Cunnison, Sonu Subin Philip, Adrian Deng, Danielle Groves, Angus M Spence, Christopher M Coleman, Jeremy R Keown, Nicole C Robb

This study characterizes the MERS-CoV replication-transcription complex and shows its structural similarity to SARS-CoV-2, with cross-species compatibility highlighting evolutionary conservation and virus-specific adaptations.

bioRxiv · Nov 2, 2026 · PreprintMicrobiology

Nucleobase Methylation Enhances SARS-CoV-2 Chain Terminator Evasion of Exonuclease Proofreading

Lin Yang, Rory Cunnison, Carmen Ka Man Tse, Tiantian Xu, Buyu Zhang, Rick Xinzhou Xu, Benny Zhibin Liang, Xunyu Zhou, Danielle Groves, Adrian Deng, Jeremy R Keown, Daqi Yu, Mingyuan Li, Yuanliang Zhai, Billy Wai-Lung Ng, , Peter Pak‐Hang Cheung

This study identifies 5-methyl-3'-dUTP as a nucleoside analogue that effectively terminates RNA chains and resists SARS-CoV-2 exoribonuclease proofreading.

bioRxiv · Sep 20, 2024 · PreprintMicrobiology

periscope: Sub-Genomic RNA Identification in SARS-CoV-2 Genomic Sequencing Data

Matthew D. Parker, Benjamin B. Lindsey, Shay Leary, Silvana Gaudieri, Abha Chopra, Matthew Wyles, Adrienn Angyal, Luke R. Green, Paul Parsons, Rachel M Tucker, Rebecca Brown, Danielle Groves, Katie Johnson, Laura Carrilero, Joe Heffer, , Thushan I. de Silva

Periscope identifies and quantifies sub-genomic RNAs in SARS-CoV-2 genomic data, detecting canonical and non-canonical sgRNAs with high fidelity.

Genome Research · Apr 1, 2021Peer-reviewedBioinformatics