Author

Sarath Ranganathan

Royal Children's HospitalORCID 0000-0002-6975-0307Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:scRNA-seq· 2 Approach:benchmark study· 1 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Alicia OshlackiD· 2 shared George HowittiD· 2 shared Jovana MaksimoviciD· 2 shared Melanie R. NeelandiD· 2 shared Peter F. HickeyiD· 2 shared Shivanthan ShanthikumariD· 2 shared Anne SenabouthiD· 1 shared Casey J. A. AnttilaiD· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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2 shared papersBioinformatics

Alicia OshlackORCID

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2 papers

Recent·Most cited

Benchmarking single-cell hashtag oligo demultiplexing methods

George Howitt, Yuzhou Feng, Lucas E. Tobar, Dane Vassiliadis, Peter F. Hickey, Mark A. Dawson, Sarath Ranganathan, Shivanthan Shanthikumar, Melanie R. Neeland, Jovana Maksimovic, Alicia Oshlack

This study benchmarks seven HTO demultiplexing tools using datasets with genetic variant-based ground truth, finding similar performance on high-quality data but poor performance on lower quality data for bimodal distribution methods.

NAR Genomics and Bioinformatics · Sep 19, 2023Peer-reviewedBioinformatics

Single-cell atlas of bronchoalveolar lavage from preschool cystic fibrosis reveals new cell phenotypes

Jovana Maksimovic, Shivanthan Shanthikumar, George Howitt, Peter F. Hickey, William Wing Ho Ho, Casey J. A. Anttila, Daniel V. Brown, Anne Senabouth, Dominik C. Kaczorowski, Daniela Amann‐Zalcenstein, Joseph E. Powell, Sarath Ranganathan, Alicia Oshlack, Melanie R. Neeland

The paper uses scRNA-seq and flow cytometry to identify novel immune and epithelial cell populations in preschool CF patients' bronchoalveolar lavage.

bioRxiv · Jun 17, 2022 · PreprintSystems Biology