NeurosciencebioRxivPreprint
Local control of dopamine release in nucleus accumbens gates opioid withdrawal aversion
Matthew B. Pomrenze, Jason Tucciarone, Gavin C. Touponse…·Robert C. Malenka
The paper identifies Tshz1 neurons in the nucleus accumbens as critical for withdrawal aversion by modulating dopamine release and mGluR8 activity, offering a new therapeutic target for opioid use disorder.
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