Jason Tucciarone

Specific basal ganglia, amygdala, and cortical neurons are associated with borderline personality disorder (BPD)

The paper identifies specific brain cell types, LAMP5 interneurons and D2 medium spiny neurons, associated with borderline personality disorder (BPD).

Local control of dopamine release in nucleus accumbens gates opioid withdrawal aversion

The paper identifies Tshz1 neurons in the nucleus accumbens as critical for withdrawal aversion by modulating dopamine release and mGluR8 activity, offering a new therapeutic target for opioid use disorder.

Habenular μ-opioid receptor knockout and chronic systemic receptor blockade promote negative affect and heighten nociceptive sensitivity

This study shows that chronic MOR blockade or habenular MOR knockout increases anxiety and pain sensitivity in mice.

Striatal dopamine integrates cost, benefit and motivation

This study shows that striatal dopamine release encodes cost, benefit, and motivation during operant tasks, with motivation inversely correlated with reward-evoked dopamine.

Genetic dissection of glutamatergic neuron subpopulations and developmental trajectories in the cerebral cortex

The paper develops genetic tools to dissect glutamatergic neuron subpopulations and their developmental trajectories in the cerebral cortex.

Genetic Single Neuron Anatomy reveals fine granularity of cortical interneuron subtypes

The paper uses genetic labeling and high-resolution microscopy to reveal fine-grained subtypes of cortical interneurons in mice, showing distinct connectivity patterns.

Selective Inhibitory Control Of Pyramidal Neuron Ensembles And Cortical Subnetworks By Chandelier Cells

This paper shows that chandelier cells selectively inhibit pyramidal neurons projecting to the basolateral amygdala, shaping communication between cortical networks.