Uhn‐Soo Cho

This paper introduces a graphene-based affinity cryo-EM grid (GFD-A) for capturing endogenous protein complexes, achieving resolutions of 2.71 Å for tagged proteins and 3.0–3.9 Å for endogenous RNase MRP and RNase P.

The paper identifies neuron-specific microexon splicing in chromatin regulators, showing that PHF21A loses DNA-binding function in neurons while retaining H3K4me0 recognition, contributing to brain development.