Coevolution of neoplastic and non-neoplastic reactive astrocyte states converges on mesenchymal-like and injury-response programs during murine glioblastoma progression and post-radiotherapy recurrence
David Lindgren, Rebecca Rosberg, Karolina I. Smoląg…·Alexander Pietras
The paper maps transcriptional changes in astrocyte and tumor cell states during glioblastoma progression and recurrence, identifying reactive astrocyte-like tumor cells associated with radioresistance.