Mira Krendel

Myo1e/f regulate phagocytic podosomes to promote efficient cup closure in macrophages

This study shows that Myo1e/f regulate phagocytic podosomes and the phagocytic ring to ensure efficient cup closure in macrophages.

Disease-associated amino acid substitutions outside canonical motor motifs impair Myo1e localization and activity

This study shows that two MYO1E mutations, A92E and G562R, impair Myo1e localization and function, contributing to steroid-resistant nephrotic syndrome.

Semi-automated reconstruction of glomerular architecture from 3D confocal microscopy data

This study introduces a semi-automated method to segment and analyze glomerular architecture from 3D confocal microscopy data, reducing manual effort and improving standardization.

Myo1e/f at the podosome base regulate podosome dynamics and promote macrophage migration

This study identifies Myo1e and Myo1f as regulators of podosome dynamics and macrophage migration by localizing to the podosome base.