Klaus Martin Kortüm

This study shows that melphalan treatment causes oxidative stress in T cells, reducing CD4+ naive T cells in high-risk multiple myeloma patients.

The paper develops an optimized immunolabeling protocol to quantify endogenous membrane receptor stoichiometry using single-molecule localization microscopy on Jurkat T cells and primary multiple myeloma cells.

This study investigates bortezomib-induced neuropathy in rats and patients, showing that early toxicity targets the blood nerve barrier, which can recover through upregulation of netrin-1.