Author

Mara John

Philipps University of MarburgORCID 0000-0001-7147-405XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Cancer Biology· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Angela RiedeliD· 2 shared Arpa AintablianiD· 2 shared Werner SchmitziD· 2 shared Alexander BrehmiD· 1 shared Ana Cetkovic· 1 shared Andrea NistiD· 1 shared Angelika Wolf· 1 shared Anneli Gebhardt-Wolf· 1 shared

Activity by Year

2021-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCancer Biology

Angela RiedelORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintJul 23, 2026

MYC/MIZ1 suppression of lysosomal protein degradation drives immune evasion in pancreatic ductal adenocarcinoma

Bastian Krenz, Toshitha Kannan, Greta Mattavelli…·Martin Eilers

This study shows that MYC suppresses lysosomal protein degradation in pancreatic ductal adenocarcinoma, promoting immune evasion by altering amino acid availability and immune cell responses.

DOI 10.64898/2026.07.23.740267

mousebulk RNA-seq

𝕏 PostBluesky

Cancer BiologybioRxivPreprintJun 11, 2026

Profound CD4+ T-Cell Reprogramming by Melphalan-Driven Oxidative Stress in High-Risk Multiple Myeloma

Mara John, Nazia Afrin, Xiang Zhou…·Angela Riedel

This study shows that melphalan treatment causes oxidative stress in T cells, reducing CD4+ naive T cells in high-risk multiple myeloma patients.

DOI 10.64898/2026.06.08.730835

humanflow cytometry

𝕏 PostBluesky

Molecular BiologybioRxivPreprintJun 3, 2021

RNA inhibits dMi-2/CHD4 chromatin binding and nucleosome remodelling

Ikram Ullah, Clemens Thölken, Yichen Zhong…·Alexander Brehm

The paper shows RNA inhibits dMi-2/CHD4 chromatin binding and nucleosome remodelling by competing with nucleosome substrates, suggesting an evolutionary conserved mechanism.

DOI 10.1101/2021.06.03.446896

DrosophilaChIP-seq

𝕏 PostBluesky