Arpa Aintablian

This study shows that MYC suppresses lysosomal protein degradation in pancreatic ductal adenocarcinoma, promoting immune evasion by altering amino acid availability and immune cell responses.

This study shows that melphalan treatment causes oxidative stress in T cells, reducing CD4+ naive T cells in high-risk multiple myeloma patients.

This study shows glycosylated GM-CSF expands immunosuppressive B-1b plasma cells and promotes regulatory functions, while non-glycosylated GM-CSF drives pro-inflammatory responses.

The paper shows that Mtb immunization protects against BCG infection despite inducing M-MDSC, and ATRA reduces M-MDSC to enhance immunity.