Angela Riedel

The paper identifies extracellular glutathione catabolism as a driver of metastasis by enabling proliferation and oxidative stress resistance in metabolically challenging microenvironments.

This study shows that MYC suppresses lysosomal protein degradation in pancreatic ductal adenocarcinoma, promoting immune evasion by altering amino acid availability and immune cell responses.

This study shows that melphalan treatment causes oxidative stress in T cells, reducing CD4+ naive T cells in high-risk multiple myeloma patients.

This study identifies blood endothelial cells in secondary lymphoid organs as key APCs that prime donor CD4 T cells, leading to acute graft-versus-host disease.