N-terminal toxin signal peptides efficiently load therapeutics into a natural nano-injection system
Eva Maria Steiner, Rooshanie N. Ejaz, Claudia S. Kielkopf, Mar Pérez‐Ruiz, Leyre Marín-Arraiza, Ivo Alexander Hendriks, Jakob Nybo Nissen, Irina Pozdnyakova, Tillmann Pape, Alice Regaiolo, Kira Götz, Ralf Heermann, Simon Rasmussen, Michael Lund Nielsen, Nicholas M. I. Taylor
This study identifies an N-terminal signal peptide that enables efficient loading of therapeutics into the Afp nano-injection system for targeted delivery.
bioRxiv · Nov 13, 2023 · PreprintMolecular Biology