Karen Sandell Sfanos

Subclonal Complete Loss of CDKN1B as a Common Genomic Alteration in Prostate Cancer: Associations with Race and Prostate Cancer Outcomes

The paper examines subclonal complete loss of CDKN1B in prostate cancer, finding higher prevalence in African American individuals and associations with worse outcomes.

Use of Droplet Digital PCR for Consistent Detection of TMPRSS2:ERG Gene Fusion Transcripts Initiated In Vitro

This study develops a ddPCR method to detect low-abundance TMPRSS2:ERG gene fusion transcripts in prostate cancer cells and evaluates potential initiators of these fusions.

An expanded metabolic pathway for androgen production by host-associated bacteria

This study identifies a bacterial pathway for androgen production, showing that gut and urinary bacteria can convert androstenedione to epitestosterone and testosterone, which promote prostate cancer growth.

Incorporation of data from multiple hypervariable regions when analyzing bacterial 16S rRNA sequencing data

The paper presents an analysis pipeline for integrating data from multiple hypervariable regions in 16S rRNA sequencing and applies it to a clinical cohort.