Author

Yao Zhang

Michigan State UniversityORCID 0000-0002-7017-3586Unclaimed ORCID profile · follow to get notified of new preprints

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Yao Zhang3 papers · Michigan State University

Biology Disciplines

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Biochemistry· 3

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 3 Approach:statistical model· 2 Assay:structural biology· 2 Approach:experimental assay· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1

Frequent Co-Authors

Jian Ping HuiD· 3 shared Hongyan Zhao· 2 shared Kenneth M. MerziD· 2 shared Majid JafariiD· 2 shared Dexin SuiiD· 1 shared Luca SagrestiiD· 1 shared Tianqi WangiD· 1 shared Tianqi Wang· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

9 top collaborators · 24 mutual co-author links

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3 shared papersBiochemistry

Jian Ping HuORCID

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3 papers

Recent·Most cited

Symmetry Analysis and Ancestral Sequence Reconstruction Reveal a Symmetrical Translocation Pathway and Activity Determinants of ZIP Metal Transporter

Yao Zhang, Tianqi Wang, Hongyan Zhao, Jian Ping Hu

This study uses symmetry analysis and ancestral sequence reconstruction to uncover the symmetric translocation pathway and activity determinants of ZIP metal transporters.

Protein Science · Sep 16, 2026Peer-reviewedBiochemistry

An N-terminal amphipathic helix governs activity and conformational dynamics of Nramp metal transporters

Majid Jafari, Hongyan Zhao, Yao Zhang, Tianqi Wang, Kenneth M. Merz, Jian Ping Hu

This study investigates the role of an N-terminal amphipathic helix in Nramp transporters, showing it regulates conformational dynamics and metal ion transport.

Journal of Biological Chemistry · Jun 9, 2026Peer-reviewedBiochemistry

Molecular insights into substrate translocation in an elevator-type metal transporter

Yao Zhang, Majid Jafari, Tuo Zhang, Dexin Sui, Luca Sagresti, Kenneth M. Merz, Jian Ping Hu

This study investigates the mechanism of metal substrate translocation in the ZIP transporter BbZIP using structural, biochemical, and computational methods, revealing unique conformational changes and transport dynamics.

Nature Communications · Nov 7, 2024Peer-reviewedBiochemistry