Author

Majid Jafari

Michigan State UniversityORCID 0000-0001-5233-6882Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 2 Assay:structural biology· 2 Approach:experimental assay· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1 Approach:statistical model· 1

Frequent Co-Authors

Jian Ping HuiD· 2 shared Kenneth M. MerziD· 2 shared Yao ZhangiD· 2 shared Dexin SuiiD· 1 shared Hongyan Zhao· 1 shared Luca SagrestiiD· 1 shared Tianqi Wang· 1 shared Tuo ZhangiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 22 mutual co-author links

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2 shared papersBiochemistry

Jian Ping HuORCID

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2 papers

Recent·Most cited

BiochemistryJournal of Biological ChemistryPeer-reviewedJun 9, 2026

An N-terminal amphipathic helix governs activity and conformational dynamics of Nramp metal transporters

Majid Jafari, Hongyan Zhao, Yao Zhang…·Jian Ping Hu

This study investigates the role of an N-terminal amphipathic helix in Nramp transporters, showing it regulates conformational dynamics and metal ion transport.

DOI 10.1016/j.jbc.2026.113243

humanstructural biology

𝕏 PostBluesky

BiochemistryNature CommunicationsPeer-reviewedNov 7, 2024

Molecular insights into substrate translocation in an elevator-type metal transporter

Yao Zhang, Majid Jafari, Tuo Zhang…·Jian Ping Hu

This study investigates the mechanism of metal substrate translocation in the ZIP transporter BbZIP using structural, biochemical, and computational methods, revealing unique conformational changes and transport dynamics.

12 citations

structural biologyexperimental assay

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