An N-terminal amphipathic helix governs activity and conformational dynamics of Nramp metal transporters
Majid Jafari, Hongyan Zhao, Yao Zhang, Tianqi Wang, Kenneth M. Merz, Jian Ping Hu
This study investigates the role of an N-terminal amphipathic helix in Nramp transporters, showing it regulates conformational dynamics and metal ion transport.
Journal of Biological Chemistry · Jun 9, 2026Peer-reviewedBiochemistry