Author

Lucile Broséus

Centre National de la Recherche ScientifiqueORCID 0000-0002-7018-2124Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 2 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 1 Research Focus:dimensionality reduction· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:long-read sequencing· 1

Frequent Co-Authors

William RitchieiD· 2 shared Alba Hernangomez‐LaderasiD· 1 shared Amaia IrizariD· 1 shared Andrew OldfieldiD· 1 shared Ariadna Cilleros‐PortetiD· 1 shared Aubin Thomas· 1 shared Barbara HeudeiD· 1 shared Carmen J. MarsitiD· 1 shared

Activity by Year

2020-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersBioinformatics

William RitchieORCID

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Author profile →

3 papers

Recent·Most cited

Placental DNA methylation captures shared and trait-specific genetic susceptibility across complex health conditions

Ariadna Cilleros‐Portet, Itziar González‐Moro, Hachem Saddiki, Sergi Marí, Todd M. Everson, Alba Hernangomez‐Laderas, Lucile Broséus, Jörg Tost, Marta Cosín‐Tomás, Marika Groleau, Darina Czamara, Manuel Lozano, Ke Hao, Johanna Tuhkanen, M. Daniele Fallin, , Nora Fernández‐Jiménez

This study constructs a high-resolution placental mQTL resource and investigates how placental DNA methylation relates to early- and later-life traits and their shared vulnerability.

medRxiv · Jul 9, 2026 · PreprintGenetic & Genomic Medicine

TALC: Transcript-level Aware Long Read Correction

Lucile Broséus, Aubin Thomas, Andrew Oldfield, Dany Séverac, Emeric Dubois, William Ritchie

TALC improves long-read transcriptome correction by modeling RNA expression and isoform representation, enhancing downstream RNA-seq accuracy.

Bioinformatics · Jul 10, 2020Peer-reviewedBioinformatics

S-IRFindeR: stable and accurate measurement of intron retention

Lucile Broséus, William Ritchie

S-IRFindeR improves accuracy and consistency in measuring intron retention by addressing biases in existing methods.

bioRxiv · Jun 25, 2020 · PreprintBioinformatics