Tao Long

Rapid Liquid Chromatography-Mass Spectrometry (rLC-MS) for Deep Metabolomics Analysis of Population Scale Studies

The paper introduces a high-throughput rLC-MS system for metabolomics analysis, demonstrating its ability to capture metabolic variation in large human populations and predict metabolic aging.

Genome-wide association study reveals shared and distinct genetic architecture underlying fatty acid and bioactive oxylipin metabolites in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL)

This study conducts a GWAS on fatty acids and oxylipins in HCHS/SOL participants, identifying 19 genetic loci and shared/distinct genetic architecture.

Genome-wide association and Mendelian randomization analysis prioritizes bioactive metabolites with putative causal effects on common diseases

This study identifies 118 genetic loci associated with 2,319 metabolite features and finds 46 causal effects of metabolites on common diseases using genome-wide association and Mendelian randomization.

A high-resolution pipeline for 16S-sequencing identifies bacterial strains in human microbiome

HiMAP improves bacterial strain identification in human microbiome 16S-sequencing data, achieving higher accuracy than existing pipelines.