Marta Brożyńska

This study identifies 667 genetic loci associated with lipid species and links 186 of them to coronary artery disease through integrative lipidomics and genomics.

In 5,959 Finns with genotypes and stool metagenomes, GWAS found 583 independent SNP-taxon associations; dairy intake modified LCT effects on Bifidobacterium, and ABO-linked Faecalicatena lactaris tracked secretor status.

This study identifies 118 genetic loci associated with 2,319 metabolite features and finds 46 causal effects of metabolites on common diseases using genome-wide association and Mendelian randomization.

The paper identifies alpha-1 antitrypsin as a key contributor to GlycA's predictive power for disease risk and mortality across multiple conditions.

This study investigates eQTL study design and analysis, finding that FDR control inflates false discoveries and effect sizes are overestimated, with a proposed bootstrap method to improve accuracy.

This paper develops a genomic risk score for coronary artery disease using 1.7 million variants and tests it in UK Biobank, showing it outperforms conventional risk factors in predicting CAD risk.

The paper identifies three distinct immune development trajectories in childhood using unsupervised clustering, revealing a high-risk atopic cluster associated with allergic diseases.