Bharat Thyagarajan

The paper examines the relationship between erythrocyte count and mortality in older adults, finding a critical threshold below which mortality risk sharply increases.

The paper identifies epistatic interactions between HK1 and GCK genes affecting HbA1c levels using Bayesian methods and confirms findings in independent studies.

This study examines how circulating inflammatory proteins change with gestational age in pregnancy and identifies associations with maternal and fetal characteristics.

This study examines the longitudinal relationship between epigenetic aging and cognitive aging in Hispanic/Latino adults, finding that increased age acceleration is linked to lower cognitive function and higher risk of MCI.

GEM-Net constructs multi-modal gene networks using harmonized omics data from the Long Life Family Study, revealing a microbiome-immune axis linked to metabolic health.

This study conducts a GWAS on fatty acids and oxylipins in HCHS/SOL participants, identifying 19 genetic loci and shared/distinct genetic architecture.

The paper identifies pleiotropic genetic factors shared between kidney function and sRAGE using GWAS and TWAS in the LLFS cohort.

The paper describes a system for quality assurance of whole genome sequence data in family studies, focusing on identifying germline variants and improving call accuracy through family-based filters.

The paper trains a computational model to deconvolve fifteen leukocyte subtypes from DNA methylation data using flow cytometry data, improving variance explanation and reducing false positives in age studies.

This study identifies over 50 new genetic loci associated with pulmonary function through a multiethnic meta-analysis of 90,715 individuals.