Author

Jason B. Wright

ORCID 0000-0002-7094-4889Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:variant calling· 2 Assay:whole-genome sequencing· 2 Organism:human· 1

Frequent Co-Authors

Alice Zheng· 1 shared Andrew Pla· 1 shared Cagdas Tazearslan· 1 shared Danielle SookiasianiD· 1 shared Donald E. SelbyiD· 1 shared Gustavo Cerqueira· 1 shared Huei-Mei Chen· 1 shared Jaime Prout· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperGenomics

Alice Zheng

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2 papers

Recent·Most cited

Hidden rAAV Breakpoints Detected Using Single-Molecule, Modified Base Sequencing

Terrence Hanscom, Luis Miguel Mendes Soares, Alice Zheng, Nathanael Bourgeois, Katherine Gall, Thia St Martin, Jason B. Wright, Donald E. Selby

The paper detects hidden DNA breakpoints in AAV vectors using modified base sequencing to improve vector design and reduce breakage.

bioRxiv · Nov 6, 2023 · PreprintGenomics

Genome-wide assays to characterize rAAV integration into human genomic DNA in vivo

Jaime Prout, Jessica R. Von Stetina, Gustavo Cerqueira, Madison Chasse, Huei-Mei Chen, Andrew Pla, Rachel Resendes, Danielle Sookiasian, Cagdas Tazearslan, Jason B. Wright, John F. Thompson

The paper develops long-read sequencing assays to detect on- and off-target integration of rAAV vectors in human genomic DNA, finding no evidence of off-target integration.

bioRxiv · Aug 22, 2023 · PreprintGenomics