Author

Cagdas Tazearslan

Albert Einstein College of Medicine

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Genetics· 1 Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

Yousin SuhiD· 3 shared Jiping YangiD· 2 shared Xizhe Wang· 2 shared Adam D. HudginsiD· 1 shared András FiseriD· 1 shared Andrew Pla· 1 shared Brandon MilhollandiD· 1 shared Daniela Contreras· 1 shared

Activity by Year

2023-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersCell Biology

Yousin SuhORCID

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Author profile →

4 papers

Recent·Most cited

In vitro heterochronic parabiosis identifies pigment epithelium-derived factor as a systemic mediator of rejuvenation by young blood

Xizhe Wang, Cagdas Tazearslan, Seungsoo Kim, Qinghua Guo, Daniela Contreras, Jiping Yang, Adam D. Hudgins, Yousin Suh

This study identifies PEDF as a systemic factor in young blood that rejuvenates cells and tissues, using an in vitro heterochronic parabiosis system.

bioRxiv · May 2, 2024 · PreprintCell Biology

Genome-wide assays to characterize rAAV integration into human genomic DNA in vivo

Jaime Prout, Jessica R. Von Stetina, Gustavo Cerqueira, Madison Chasse, Huei-Mei Chen, Andrew Pla, Rachel Resendes, Danielle Sookiasian, Cagdas Tazearslan, Jason B. Wright, John F. Thompson

The paper develops long-read sequencing assays to detect on- and off-target integration of rAAV vectors in human genomic DNA, finding no evidence of off-target integration.

bioRxiv · Aug 22, 2023 · PreprintGenomics

Identification and functional validation of an enhancer variant in the 9p21.3 locus associated with glaucoma risk and elevated expression of p16INK4a

Yizhou Zhu, Cagdas Tazearslan, Michael G. Rosenfeld, András Fiser, Yousin Suh

The paper identifies a functional variant in the 9p21.3 locus associated with glaucoma risk and shows it increases p16INK4a expression by disrupting YY1 binding.

Aging Cell · Jun 22, 2023Peer-reviewedGenetics

The regulation of Insulin/IGF-1 signaling by miR-142-3p associated with human longevity

Xifan Wang, Hwa Jin Jung, Brandon Milholland, Jinhua Cui, Cagdas Tazearslan, Gil Atzmon, Xizhe Wang, Jiping Yang, Qinghua Guo, Nir Barzilai, Paul D. Robbins, Yousin Suh

This study identifies miR-142-3p as a regulator of human longevity by modulating the insulin/IGF-1 signaling pathway in B-cells and mice.

bioRxiv · May 19, 2023 · PreprintMolecular Biology