Development and pharmacological characterization of a stable HEK293 cell model for the study of human FLT3 signaling and its pharmacological modulation
Hugo Bourki, Jean-Philippe Leyris, Sylvie Mallié, Ilana Méchaly, Pierre Sokoloff, Jean Valmier, Cyril Rivat, Hamid Moha ou Maati
The paper develops a stable HEK293 cell line expressing FLT3 for pharmacological studies and shows it effectively models FLT3 signaling and response to inhibitors.
bioRxiv · Oct 19, 2026 · PreprintCell Biology