Comprehensive Assessment of Initial Adaptation of ESBL Positive ST131 Escherichia coli to Carbapenem Exposure
William C. Shropshire, Xinhao Song, Jordan Bremer, Seokju Seo, Susana Rodriguez, Selvalakshmi Selvaraj Anand, An Q. Dinh, Micah M. Bhatti, Anna Konovalova, César A. Arias, Awdhesh Kalia, Yousif E. Shamoo, Samuel A. Shelburne
The paper assesses how ESBL-positive ST131 E. coli adapts to carbapenem exposure, finding increased ESBL gene copy numbers and Omp gene mutations correlate with resistance development.
The Journal of Infectious Diseases · Nov 27, 2024Peer-reviewedMicrobiology