Author

Anna Konovalova

The University of Texas Health Science Center at HoustonORCID 0000-0002-2238-8849Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 1 Microbiology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Organism:E. coli· 2 Approach:statistical model· 2 Assay:whole-genome sequencing· 2 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Micah M. BhattiiD· 2 shared William C. ShropshireiD· 2 shared An Q. DinhiD· 1 shared Awdhesh KaliaiD· 1 shared Benjamin Strope· 1 shared Blake HansoniD· 1 shared CA Arias· 1 shared César A. AriasiD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersMicrobiology

Micah M. BhattiORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Systems BiologybioRxivPreprintOct 22, 2025

Modeling σE biochemical network reveals context-dependent feedback control and kinetic constraints in the envelope stress response

Cristina S.D. Palma, Natalie Allen, Martynas Basevicius…·Oleg A. Igoshin

The paper models the σE biochemical network to show how transcriptional and post-translational regulation interact to control σE activity under stress, revealing context-dependent feedback mechanisms.

DOI 10.1101/2025.10.22.683963

E. colistatistical model

𝕏 PostBluesky

MicrobiologyThe Journal of Infectious DiseasesPeer-reviewedNov 27, 2024

Comprehensive Assessment of Initial Adaptation of ESBL Positive ST131 Escherichia coli to Carbapenem Exposure

William C. Shropshire, Xinhao Song, Jordan Bremer…·Samuel A. Shelburne

The paper assesses how ESBL-positive ST131 E. coli adapts to carbapenem exposure, finding increased ESBL gene copy numbers and Omp gene mutations correlate with resistance development.

4 citations

E. coliwhole-genome sequencing

𝕏 PostBluesky

GenomicsbioRxivPreprintMay 20, 2022

Systematic Analysis of Mobile Genetic Elements Mediating β-lactamase Gene Amplification in Non-Carbapenemase-Producing Carbapenem Resistant Enterobacterales Bloodstream Infections

William C. Shropshire, Anna Konovalova, Patrick M. McDaneld…·SA Shelburne

This study identifies mobile genetic elements driving β-lactamase gene amplification in non-CP-CRE bloodstream infections through genomic analysis.

DOI 10.1101/2022.05.20.492874

humanwhole-genome sequencing

𝕏 PostBluesky