Author

Barry E. DeZonia

University of Wisconsin–MadisonORCID 0000-0002-7151-8670Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1 Approach:statistical model· 1 Assay:structural biology· 1

Frequent Co-Authors

Benjamin D. HardingiD· 2 shared Chad M. RienstraiD· 2 shared Charles D. SchwietersiD· 1 shared Collin G. BorcikiD· 1 shared Dhruva D. DhavaleiD· 1 shared Elizabeth WrightiD· 1 shared Frank DelaglioiD· 1 shared Joshua A. Pierson· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersBiophysics

Benjamin D. HardingORCID

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2 papers

Recent·Most cited

In vitro-prepared A30P alpha-synuclein fibrils adopt the conserved and disease-relevant Greek key fold

Moses H. Milchberg, Owen A. Warmuth, Collin G. Borcik, Ruixian Han, Benjamin D. Harding, Barry E. DeZonia, Dhruva D. Dhavale, Joshua A. Pierson, Paul T. Kotzbauer, Elizabeth Wright, Charles D. Schwieters, Chad M. Rienstra

The paper reports the high-resolution SSNMR structure of A30P mutant alpha-synuclein fibrils, showing a conserved Greek key fold not including the mutation site, and validates a method for comparing SSNMR spectra of Asyn polymorphs.

The Journal of Physical Chemistry B · Jul 2, 2026Peer-reviewedBiophysics

Top-Down Scoring of Spectral Fitness by Image Analysis for Protein Structure Validation

Benjamin D. Harding, Barry E. DeZonia, Rajat Garg, Ziling Hu, Frank Delaglio, Timothy Grant, Chad M. Rienstra

This paper introduces BPHON, a method that uses image analysis to score the fitness of protein structures against NMR spectra without requiring full resonance assignments.

Journal of Chemical Information and Modeling · Dec 19, 2025Peer-reviewedBiophysics