Elizabeth Wright

The paper shows that injecting amplified Lewy body dementia fibrils into mice leads to fibril accumulation with LBD structure and neurodegeneration.

The paper reports the high-resolution SSNMR structure of A30P mutant alpha-synuclein fibrils, showing a conserved Greek key fold not including the mutation site, and validates a method for comparing SSNMR spectra of Asyn polymorphs.

This study uses cryo-ET and sub-tomogram averaging to analyze Ty1 virus-like particles, revealing diverse capsomere arrangements and the role of CA-CTD flexibility in VLP heterogeneity.

This study investigates the structural and biophysical properties of E. coli Dps across a pH range, revealing pH-dependent DNA binding and assembly behavior.

The paper classifies Alpha-synuclein fibril structures into two main polymorph classes using clustering and finds conserved motifs that could guide drug design.

The paper uses structural and chemical biology methods to show EX-6 binds selectively to α-synuclein fibrils in MSA tissue, with a 10-fold preference over PD tissue.

The paper introduces a microfluidic device that enables correlative fluorescence light microscopy and cryo-electron microscopy for real-time and ultrastructural analysis of cells.

This paper provides a protocol for high-resolution cryo-EM structure determination of α-synuclein fibrils, resulting in a 2.04 Å structure with new density features.

This study determines the in-situ crystalline structure of MBP-1 in eosinophil secretory granules and shows activation-dependent crystal expansion and extrusion.