Author

Martine Berthelot‐Grosjean

Centre National de la Recherche ScientifiqueORCID 0000-0002-7168-2622Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:Drosophila· 3 Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Gérard ManièreiD· 3 shared Julien RoyetiD· 3 shared Romane MillevilleiD· 3 shared Yaël GrosjeaniD· 3 shared C. Léopold KurziD· 2 shared Alix Najera Mazariegos· 1 shared Amanda-Thuy La· 1 shared Carla Jane DuvaliD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersNeuroscience

Gérard ManièreORCID

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3 papers

Recent·Most cited

NeurosciencebioRxivPreprintDec 24, 2025

Uracil-Driven ROS signals activate larval TrpA1-B neurons to prime the Drosophila adult gustatory response to bacterial signal

Romane Milleville, Gérard Manière, Martine Berthelot‐Grosjean…·C. Léopold Kurz

The paper identifies uracil as a bacterial signal that primes Drosophila adults to respond to peptidoglycan through Duox/ROS and TrpA1/Gr66a pathways in larval neurons.

DOI 10.64898/2025.12.22.695905

Drosophilaexperimental assay

𝕏 PostBluesky

NeuroscienceChemical SensesPeer-reviewedJan 1, 2025

Adult Drosophila aversion to caffeine requires a unique TrpA1 isoform and the PLC signaling cascade

Romane Milleville, Jade Gillas, Amanda-Thuy La…·C. Léopold Kurz

The paper shows that caffeine aversion in Drosophila requires the TrpA1-E isoform and PLC signaling in Gr66a+ neurons.

DOI 10.1093/chemse/bjaf058

Drosophilaexperimental assay

𝕏 PostBluesky

ImmunologybioRxivPreprintSep 26, 2024

Detection of bacteria through taste receptors primes the cellular immune response

Alix Najera Mazariegos, Gérard Manière, Léo Sillon…·Guy Tanentzapf

This study shows that Drosophila larvae use taste receptors to detect bacteria, which primes their immune system and improves survival after infection.

3 citations

Drosophilaexperimental assay

𝕏 PostBluesky