Author

Natasha C. Koussa

New York UniversityORCID 0000-0002-7169-8229Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:differential expression· 2 Assay:DNA methylation· 2 Research Focus:gene regulatory network inference· 2 Research Focus:variant calling· 2 Assay:whole-genome sequencing· 2 Organism:yeast· 2 Research Focus:genome assembly· 1

Frequent Co-Authors

Duncan J. SmithiD· 2 shared André NussenzweigiD· 1 shared Aseem Z. AnsariiD· 1 shared Ashraf MohammediD· 1 shared Colin P. TangiD· 1 shared Daphne N. KrameriD· 1 shared Frida BelinkyiD· 1 shared Gabriel E. Matos-RodriguesiD· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersMolecular Biology

Duncan J. SmithORCID

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3 papers

Recent·Most cited

Molecular BiologybioRxivPreprintJan 19, 2022

Linking Dynamic DNA Secondary Structures to Genome Instability

Gabriel E. Matos-Rodrigues, Niek van Wietmarschen, Wei Wu…·André Nussenzweig

The paper identifies dynamic DNA secondary structures in vivo that contribute to genome instability by analyzing ssDNA converted to DSBs using S1-END-seq.

3 citations

humanDNA methylation

Molecular BiologyPLoS GeneticsPeer-reviewedJan 25, 2021

Limiting DNA polymerase delta alters replication dynamics and leads to a dependence on checkpoint activation and recombination-mediated DNA repair

Natasha C. Koussa, Duncan J. Smith

This study shows that reducing DNA polymerase delta in yeast causes replication stress, genome instability, and reliance on repair pathways.

19 citations

yeastDNA methylation

Molecular BiologyPLoS GeneticsPeer-reviewedMay 7, 2020

Separable, Ctf4-mediated recruitment of DNA Polymerase α for initiation of DNA synthesis at replication origins and lagging-strand priming during replication elongation

Sarina Y. Porcella, Natasha C. Koussa, Colin P. Tang…·Duncan J. Smith

The paper investigates the role of DNA Polymerase α and Ctf4 in DNA replication initiation and lagging-strand priming in S. cerevisiae, showing distinct sensitivities to Ctf4 and Pol levels.

25 citations

yeastexperimental assay