Author

Payal P. Pratap

Scripps Research InstituteORCID 0000-0002-7170-6866Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1 Organism:rat· 1 Assay:structural biology· 1

Frequent Co-Authors

Alyana J. GranadosiD· 1 shared Andrew B. WardiD· 1 shared Andy S. TraniD· 1 shared Ashley A. LemniosiD· 1 shared Bryan S. BrineyiD· 1 shared Chiamaka A. Enemuo· 1 shared Christopher A. CottrelliD· 1 shared Daniel L. V. Bader· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperBiochemistry

Alyana J. GranadosORCID

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2 papers

Recent·Most cited

Structural basis for regulation of Frizzled-4 signaling by the co-receptor Tetraspanin-12

Alyana J. Granados, Payal P. Pratap, Kevin Alexander Estrada Alamo, Katherine J. Susa

This paper reports the structure of the FZD4-Tspan12 complex and shows how Tspan12 enhances Norrin signaling by facilitating trafficking and higher-affinity Norrin binding.

bioRxiv · Sep 25, 2025 · PreprintBiochemistry

Immunofocusing on the conserved fusion peptide of HIV envelope glycoprotein in rhesus macaques

Payal P. Pratap, Christopher A. Cottrell, James Quinn, Diane G. Carnathan, Daniel L. V. Bader, Andy S. Tran, Chiamaka A. Enemuo, Julia T. Ngo, Sara T. Richey, Hongmei Gao, Xiaoying Shen, Kelli Greene, Jonathan Hurtado, Katarzyna Kaczmarek Michaels, Elana Ben‐Akiva, , Andrew B. Ward

This study shows that targeting the conserved HIV fusion peptide with modified Env immunogens in rhesus macaques can focus immune responses on neutralizing epitopes.

npj Vaccines · Aug 20, 2025Peer-reviewedImmunology