Author

Kevin Alexander Estrada Alamo

Fred Hutch Cancer CenterORCID 0000-0002-3829-357XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1 Assay:structural biology· 1

Frequent Co-Authors

Adam NguyeniD· 1 shared Alyana J. GranadosiD· 1 shared Analisa Murray· 1 shared Anindya RoyiD· 1 shared Aritza Brizuela‐VelascoiD· 1 shared Buwei HuangiD· 1 shared Cole A. DeForestiD· 1 shared Daniel Cabrerizo‐AguadoiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperBioengineering

Adam NguyenORCID

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2 papers

Recent·Most cited

BiochemistrybioRxivPreprintSep 25, 2025

Structural basis for regulation of Frizzled-4 signaling by the co-receptor Tetraspanin-12

Alyana J. Granados, Payal P. Pratap, Kevin Alexander Estrada Alamo, Katherine J. Susa

This paper reports the structure of the FZD4-Tspan12 complex and shows how Tspan12 enhances Norrin signaling by facilitating trafficking and higher-affinity Norrin binding.

DOI 10.1101/2025.09.25.678640

structural biologyexperimental assay

𝕏 PostBluesky

BioengineeringAdvanced MaterialsPeer-reviewedJun 9, 2025

De Novo Design of Integrin α5β1 Modulating Proteins for Regenerative Medicine

Xinru Wang, Jordi Guillem‐Marti, Saurav Kumar…·David A. Baker

The paper designs de novo proteins called NeoNectins that specifically bind integrin α5β1, enhancing cell attachment and tissue integration in biomaterials.

9 citationstop 3%

protein structureexperimental assay

𝕏 PostBluesky