Gražvydas Lukinavičius

This paper introduces a near-infrared fluorogenic probe for selective detection and imaging of inorganic polyphosphates in various biological contexts.

The paper develops a fluorescent probe for visualizing HDAC6 in live cells, showing high selectivity and utility in imaging its interactions with microtubules and stress granules.

OptiFoot records protein-nucleic acid interactions using fluorescence and optical mapping, enabling spatial and genomic analysis of DNA and RNA in human cells.

This paper develops stabilized AdoMet analogues with enhanced chemical stability for enzymatic DNA labeling, achieving up to 90-fold increased half-life and retaining MTase activity.

The paper develops and evaluates regioisomer-controlled red-shifted DNA probes for in vivo imaging, finding that 5' regioisomers provide optimal performance in multiple tissues.

The paper develops a biocompatible fluorescent probe for tubulin labeling in live and fixed cells, enabling high-resolution imaging with minimal functional disruption.

The paper identifies an error-prone mechanism of parental genome unification in bovine embryos that leads to aneuploidy, with defects in nucleolar clustering correlating with embryo development failure.