Olexandr Dybkov

This study shows non-coding RNA disrupts enhancer-promoter interactions when increased, and stabilizes them when decreased, independent of transcription initiation.

The paper shows that phosphorylation of NOB1, an endoribonuclease, affects 18S rRNA processing and pre-rRNA levels during small subunit biogenesis.

The paper determines the cryo-EM structure of cytoplasmic Pol II and shows Gdown1 inhibits its transcriptional activity by blocking essential factor binding.

The paper uses Alphafold3 to predict and validate the structure of the Imp{beta}/Imp7/H1 complex, showing H1 binds to Imp7 rather than Imp{beta} and identifying key interaction regions.

The paper develops a biocompatible fluorescent probe for tubulin labeling in live and fixed cells, enabling high-resolution imaging with minimal functional disruption.

This study reveals a three-step mechanism of co-transcriptional H3K36 methylation by SETD2 through cryo-EM structures and functional analysis.

The paper introduces chemical crosslinking with mass spectrometry and a new search engine, NuXL, to identify nucleic acid-protein crosslinks at amino acid resolution, enhancing structural analysis.

This study investigates how ULK1 activity influences ATG101 auto-activation dynamics, revealing a memory mechanism that accelerates autophagy complex formation.

This study presents cryo-EM structures of Nipah virus RdRp in apo and early elongation states, revealing its architecture and RNA interaction mechanisms.

The paper reports cryo-EM structures of aberrant spliceosome intermediates in S. pombe, revealing how a helicase-protein pair maintains catalytic dormancy and facilitates disassembly.