Haploinsufficiency of autism candidate gene NUAK1 impairs cortical development and behavior
Virginie Courchet, Amanda J. Roberts, Géraldine Meyer-Dilhet, Peggy del Carmine, Tommy L. Lewis, Franck Polleux, Julien Courchet
This study shows that haploinsufficiency of the autism candidate gene Nuak1 in mice causes cortical development defects and behavioral abnormalities resembling ASD, intellectual disability, and schizophrenia.
Nature Communications · Oct 10, 2018Peer-reviewedNeuroscience