Author

Le Cheng

BGI Group (China)ORCID 0000-0002-7201-6744Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:gene regulatory network inference· 3 Approach:statistical model· 3 Research Focus:differential expression· 2 Research Focus:genome assembly· 2 Assay:whole-genome sequencing· 2 Research Focus:cell type annotation· 1 Organism:human· 1

Frequent Co-Authors

Huan LiuiD· 2 shared Sunil Kumar SahuiD· 2 shared Xin LiuiD· 2 shared Xun XuiD· 2 shared Ao CheniD· 1 shared Bin CheniD· 1 shared Bosiljka TasiciD· 1 shared C. R. Srikumari SrisailapathyiD· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersGenomics

Huan LiuORCID

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Author profile →

4 papers

Recent·Most cited

Genetic and phenotypic heterogeneity in PNPT1, MYO15A, PTPRQ and SLC12A2 variants detected among hearing impaired assortative mating families in Southern India

Paridhy Vanniya Subramanyam, Jayasankaran Chandru, Jeffrey Justin Margret, Tom Rabinowitz, Zippora Brownstein, Mathuravalli Krishnamoorthy, Karen B. Avraham, Le Cheng, Noam Shomron, C. R. Srikumari Srisailapathy

The paper identifies six variants in four genes associated with hearing loss in four South Indian families, highlighting genetic and phenotypic heterogeneity.

Annals of Human Genetics · Aug 9, 2021Peer-reviewedGenetics

Spatially resolved gene regulatory and disease vulnerability map of the adult Macaque cortex

Ying Lei, Mengnan Cheng, Zihao Li, Zhenkun Zhuang, Liang Li Wu, Yunong Sun, Lei Han, Zhi‐Hao Huang, Yuzhou Wang, Zifei Wang, Liqin Xu, Yue Yuan, Shang Liu, Taotao Pan, Jiarui Xie, , Xun Xu

The paper integrates single-cell ATAC and transcriptomic data with spatial transcriptomics to map regulatory features and disease vulnerabilities in macaque cortex.

bioRxiv · May 14, 2020 · PreprintNeuroscience

Slicing the genome of star-fruit (Averrhoa carambola L.)

Yannan Fan, Sunil Kumar Sahu, Ting Yang, Weixue Mu, Jinpu Wei, Le Cheng, Jinlong Yang, Xun Xu, Xin Liu, Ranchang Mu, Jie Liu, Jianming Zhao, Yuxian Zhao, Huan Liu

This paper presents the first draft genome of the star-fruit plant, identifying genes and conducting phylogenomic analysis to provide resources for nutritional and medicinal studies.

bioRxiv · Jan 28, 2020 · PreprintGenomics

Chromosome level draft genomes of the fall armyworm, Spodoptera frugiperda (Lepidoptera: Noctuidae), an alien invasive pest in China

Huan Liu, Tianming Lan, Dongming Fang, Furong Gui, Hongli Wang, Wei Guo, Xiaofang Cheng, Yue Chang, Shuqi He, Lihua Lyu, Sunil Kumar Sahu, Le Cheng, Haimeng Li, Ping Liu, Guangyi Fan, , Xin Liu

This study assembled two chromosome-scale genomes of the fall armyworm in China, revealing gene family expansions and population origins to aid in pest management.

bioRxiv · Jun 15, 2019 · PreprintGenomics