Author

Selene M. Clay

University of ChicagoORCID 0000-0002-7204-9570Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:GWAS / association mapping· 1

Frequent Co-Authors

Carole OberiD· 2 shared Daniel J. JacksoniD· 2 shared James E. GerniD· 2 shared Matthew C. AltmaniD· 2 shared Agustin CalatroniiD· 1 shared Andrew H. LiuiD· 1 shared Anne I. SperlingiD· 1 shared Cara Lynn Hrusch· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersGenetic & Genomic Medicine

Carole OberORCID

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2 papers

Recent·Most cited

Multi-omic association study identifies DNA methylation-mediated genotype and smoking exposure effects on lung function in children living in urban settings

Matthew Dapas, Emma E. Thompson, William Wentworth-Sheilds, Selene M. Clay, Cynthia M. Visness, Agustin Calatroni, Joanne E. Sordillo, Diane R. Gold, Robert A. Wood, Melanie Makhija, Gurjit K. Khurana Hershey, Michael G. Sherenian, Rebecca S. Gruchalla, Michelle Ann Gill, Andrew H. Liu, , Carole Ober

This study identifies a genetic variant associated with reduced lung function in urban children and shows its mediation by DNA methylation linked to smoking exposure.

PLoS Genetics · Jan 13, 2023Peer-reviewedGenetic & Genomic Medicine

Asthma-associated variants induce IL33 differential expression through a novel regulatory region

Ivy Aneas, Donna C. Decker, Chanie L. Howard, Débora R. Sobreira, Noboru J. Sakabe, Kelly M. Blaine, Michelle M. Stein, Cara Lynn Hrusch, Lindsey E. Montefiori, Juan J. Tena, Kevin M. Magnaye, Selene M. Clay, James E. Gern, Daniel J. Jackson, Matthew C. Altman, , Marcelo A. Nóbrega

The paper identifies a regulatory region near the IL33 gene that influences asthma risk through allele-specific expression and OCT-1 binding.

bioRxiv · Sep 9, 2020 · PreprintGenomics